NIPH Clinical Trials Search

Efficacy of ACI in ESD

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	Colorectal lesion and duodenal adenomatous lesion
Date of first enrollment	05/02/2026
Target sample size	104
Countries of recruitment
Study type	Interventional
Intervention(s)	ESD is performed using WLI in the WLI group and ACI in the ACI group.

Outcome(s)

Primary Outcome	Number of events of intraoperative bleeding requiring endoscopic hemostasis and muscular injury.
Secondary Outcome	i) Procedure time ii) Resection outcome and adverse events iii) Rate of patients treated with hemostatic forceps

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	Not applicable
Gender	Both
Include criteria	i) Patient with colorectal or duodenal adenomatous lesion considered difficult to resect en bloc by snare on endoscopic diagnosis. ii) 18 years of age or older iii) Patienst who have been fully informed consen t.
Exclude criteria	Colorectal ESD group i) Suspected of invasive cancer ii) Suspected of recurrence polyps iii) Inflammatory Bowel Disease (IBD) iv) Familial Adenomatous Polyposis (FAP) v) Patients who have difficulty with withdrawal of medication in accordance with antithrombotic dru g guideline vi) Patients on dialysis vii) Patients who judged as inappropriate candida te by the chief medical examine Duodenal ESD or LECS group i) Suspected of invasive cancer ii) Suspected of recurrence polyps iii) Lesions on the duodenal papilla iv) Patients who have difficulty with withdrawal of medication in accordance with antithrombotic dru g guideline v) Patients on dialysis vi) Patients who judged as inappropriate candida te by the chief medical examine