NIPH Clinical Trials Search

A prospective study on the clinical efficacy of Narrow-band UVB Therapy for chronic prurigo

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	Prurigo nodularis and chronic prurigo (including prurigo chronica multiformis)
Date of first enrollment	24/12/2025
Target sample size	30
Countries of recruitment
Study type	Interventional
Intervention(s)	To evaluate the efficacy and safety of NB-UVB therapy for prurigo patients (prurigo nodularis and prurigo chronica multiformis) .

Outcome(s)

Primary Outcome	Percentage change (%) in skin rash area at 12 weeks of NB-UVB therapy
Secondary Outcome	Pruritus VAS Score, EASI Score (Eczema Area and Severity Index), Hematologic and Immunologic Markers, Incidence of Adverse Events, Change rate in skin area at each time point other than 12 weeks

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	Not applicable
Gender	Both
Include criteria	Patients clinically diagnosed with nodular prurigo/prurigo chronica multiformis who have resistance to conventional treatment (topical steroids and antihistamines)
Exclude criteria	Patients undergoing treatment with biological agents or JAK inhibitors, patients with a history of skin cancers, patients with photosensitivity