NIPH Clinical Trials Search

Safety and Effectiveness of Rebosis in orthognathic surgery

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	Jaw deformity
Date of first enrollment	13/01/2026
Target sample size	30
Countries of recruitment
Study type	Interventional
Intervention(s)	Rebosis is inserted into the bone gap created by Lefort I osteotomy.

Outcome(s)

Primary Outcome	Incidence of wound infection and wound dehiscence
Secondary Outcome	Bone union, degree of bone hardening, and reduction of defect area at 6 and 12 months after surgery

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	Not applicable
Gender	Both
Include criteria	1) Patients with jaw deformity who will undergo LeFort I osteotomy within nine months of approval by jRCT and who are 18 years of age or older at the time of obtaining informed consent. 2) Patients who have received a sufficient explanation of this study, fully understood the study, and voluntarily provided written informed consent.
Exclude criteria	1) Patients who have extremely poor oral hygiene 2) Patients with unmanageable severe systemic disease, bleeding disease, endocrine disease 3) Drug, alcohol, nicotine addiction patients 4) Patients with diseases that require regular steroid or immunosuppressants administration 5) Patients receiving bone-modifying drugs 6) In addition, patients who are judged by the principal investigator and the investigator to be inappropriate as research subjects