NIPH Clinical Trials Search

Focused Mindfulness Walking and at-home tDCS: An Exploratory Study

Basic Information

Recruitment status	Pending
Health condition(s) or Problem(s) studied	Mild depression or adjustment disorder
Date of first enrollment	28/04/2026
Target sample size	5
Countries of recruitment
Study type	Interventional
Intervention(s)	FMW-tDCS (Mindfulness: Focused Mindfulness Walking [FMW]) and tDCS (Transcranial Direct Current Stimulation [tDCS]) simultaneously

Outcome(s)

Primary Outcome

To confirm the occurrence of adverse effects (including headache, skin discomfort, tinnitus, fatigue, anxiety, and manic symptoms) and to identify potential challenges in the home application of FMW-tDCS.

Secondary Outcome

- the occurrence of adverse reactions and identify any difficulties in performing FMW-tDCS at home. - Adjustment Disorder New Module 20 (ADNM-20) - State Trait Anxiety Inventory (STAI) - Five Facet Mindfulness Questionnaire (FFMQ) - Perceived Stress Scale (PSS) - Work Productivity and Activity Impairment Questionnaire (WPAI) - Quick Inventory of Depressive Symptomatology (QIDS-J) - Social Adaptation Self-evaluation Scale (SASS-J) - Young Mania Rating Scale (YMRS) - Hamilton Depression Rating Scale 17 - Goal Attainment Scale for Depression (GAS-D) - Edinburgh Handeadness Invebntory - THINC-it - EEG - Interview - Number of steps / Heart rate

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	< 65age old
Gender	Both
Include criteria	- Individuals aged 18 years or older and younger than 65 years. - Both male and female participants are eligible. - At the beginning of the screening period, patients who are diagnosed as either mild depression or adjustment disorder, without suicidal ideation, and who are receiving outpatient treatment (with a Hamilton Depression Rating Scale [HAMD-17] score of 5 to 16) - Right-handed individuals (to minimize the influence of inter-individual differences in the dominant hemisphere, confirmed by the Edinburgh Handedness Inventory). - Individuals who, after receiving sufficient explanation regarding participation in this study, have fully understood the information and have provided written informed consent of their own free will.
Exclude criteria	1. Individuals with metal implants (excluding titanium) in the brain or skin. 2. Individuals with metal devices (e.g., pacemakers) implanted in the body. 3. Individuals with a history of head surgery or other surgical procedures. 4. Individuals who have experienced head trauma or impaired consciousness due to head trauma. 5. Individuals with skin conditions or disorders in the area of stimulation. 6. Individuals with a history of epileptic seizures. 7. Individuals with a history of syncope (fainting). 8. Individuals who are pregnant or possibly pregnant. 9. Individuals with a history of stroke or other central nervous system disorders. 10. Individuals with a history of psychiatric disorders, such as schizophrenia, bipolar disorder, or substance abuse. 11. Individuals deemed unsuitable as research subjects by the principal investigator.