NIPH Clinical Trials Search

Effects of different surgical stapler on pulmonary artery stump

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	Lung neoplasms
Date of first enrollment	09/01/2025
Target sample size	55
Countries of recruitment
Study type	Interventional
Intervention(s)	Selection of cartridges used in surgical staplers

Outcome(s)

Primary Outcome

Presence or absence of vascular membrane crushing in the adventitia, media, or intima as identified by pathological evaluation.

Secondary Outcome

Presence or absence of oozing from the excised pulmonary artery stump (intraoperative finding), tissue compression score (pathological finding) (Thompson SE, et al. Initial assessment of mucosal capture and leak pressure after gastrointestinal stapling in a porcine model. Obes Surg. 2018;28(11):3446-53.), operation time, amount of bleeding, presence or absence of compression hemostasis, presence or absence of use of tissue adhesive or closure agents, etc., presence or absence of use of intraoperative blood transfusion, duration of drain placement, postoperative hospital stay, and presence or absence of postoperative complications

Key inclusion & exclusion criteria

Age minimum	>= 20age old
Age maximum	Not applicable
Gender	Both
Include criteria	1. Patients who are 20 years of age or older at the time of obtaining consent 2. Patients who are able to obtain written consent, comply with the rules for participation in the study, undergo medical examinations and tests as stipulated in the research protocol, and report symptoms and other information. 3. Patients who require pulmonary resection (segmentectomy or lobectomy) with pulmonary artery dissection, such as malignant lung tumors (primary lung cancer, metastatic lung cancer, malignant lymphoma, etc.), benign lung tumors, pulmonary arteriovenous malformations, inflammatory lung disease, etc.
Exclude criteria	1. Patients who have undergone thoracic surgery (partial lung resection, segmentectomy, lobectomy, mediastinal tumor resection, etc.) on the same side as the surgical operation side. 2. Patients who live in a remote area or otherwise have difficulty in making scheduled hospital visits or follow-up examinations.