NIPH Clinical Trials Search

Evaluation of Oxytocin Receptor PET Whole-Body Scans in Healthy Volunteers

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	none
Date of first enrollment	18/03/2026
Target sample size	6
Countries of recruitment
Study type	Interventional
Intervention(s)	Healthy volunteers will receive intravenous administration of the novel PET tracer [11C]OCS5, followed by whole-body and brain dynamic imaging using a PET scanner.

Outcome(s)

Primary Outcome	Changes in Whole-Body Distribution Following Administration of the OXTR-PET Tracer [11C]OCS5 Injection
Secondary Outcome	Safety and Exposure Levels of the OXTR-PET Tracer [11C]OCS5

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	< 55age old
Gender	Both
Include criteria	(1) Males and females aged 18 years or older but under 55 years at the time of consent acquisition (2) Healthy individuals with no past medical history (excluding infectious diseases that do not leave sequelae) or current medical conditions (3) Individuals for whom written consent to participate in this study has been obtained from the subject themselves
Exclude criteria	(1)Individuals diagnosed with a mental disorder or intellectual disability (2) Use of psychotropic medications within the past 6 months (3) Pregnant individuals, breastfeeding individuals, or individuals who may be pregnant (4) History of hypersensitivity to oxytocin (5) History of epileptic seizures or head trauma with loss of consciousness lasting 5 minutes or longer (6) History of alcohol-related disorders or other substance-related disorders (7)Individuals with serious concomitant medical conditions (8) Individuals with severe allergies or idiosyncrasies, such as anaphylaxis (9) Individuals unable to agree to use contraception during the study period (10) Individuals who participated in another PET study (involving radiation exposure) within one year prior to obtaining consent (11) Other individuals deemed ineligible for this study by the principal investigator (or co-investigator)