NIPH Clinical Trials Search

A Study to Confirm the Extent of Hemolysis and Renal Impairment in Radiofrequency Ablation for Atrial Fibrillation

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	Atrial fibrillation
Date of first enrollment	06/08/2025
Target sample size	30
Countries of recruitment
Study type	Observational
Intervention(s)

Outcome(s)

Primary Outcome	Degree of increase in free hemoglobin in T2, T3, and T4 Degree of increase in creatinine in T2, T3, and T4 Incidence of kidney injury stage1 or higher according to KDIGO clinical guidelines
Secondary Outcome	Degree of elevation in total bilirubin and LDH during T2, T3, and T4 Degree of decrease in serum hemoglobin during T2, T3, and T4 Degree of elevation in BUN during T2, T3, and T4 Frequency of patients with haptoglobin levels falling below the detection limit on the day after surgery

Key inclusion & exclusion criteria

Age minimum	Not applicable
Age maximum	Not applicable
Gender
Include criteria	Patients undergoing initial radiofrequency catheter ablation for atrial fibrillation
Exclude criteria	Patients meeting any of the following criteria: Currently participating in another clinical trial or clinical research (interventional study) Left ventricular ejection fraction =<35% Left atrial diameter >=55 mm Renal impairment with serum creatinine >=1.5 mg/dL Post-valvular surgery (including catheter-based treatment) Post-Maze surgery Severe valvular disease Active malignant neoplasm