NIPH Clinical Trials Search

The effects of anesthetics on hemodynamics during EVAR: RCT

Basic Information

Recruitment status	Complete
Health condition(s) or Problem(s) studied	Abdominal Aortic Aneurysm
Date of first enrollment	30/11/2022
Target sample size	31
Countries of recruitment
Study type	Interventional
Intervention(s)	Randomization will be conducted to evaluate the use of remimazolam or sevoflurane as an anesthetic maintenance agent.

Outcome(s)

Primary Outcome	AUT (Area Under Threshold), which combines the duration and magnitude of periods when the average blood pressure is below 65 mmHg
Secondary Outcome	Number of episodes of hypotension Total duration of hypotension Occurrence of severe hypotension (mean arterial pressure < 50 mmHg) Amount of vasopressor used during surgery

Key inclusion & exclusion criteria

Age minimum	Not applicable
Age maximum	Not applicable
Gender	Both
Include criteria	31 patients with abdominal aortic aneurysms undergoing EVAR (Endovascular Aneurysm Repair) under general anesthesia
Exclude criteria	(1) Patients who are in atrial fibrillation at the time of admission to the operating room and cannot be evaluated for appropriate heart rate variability (2) Dialysis patients (3) Patients taking benzodiazepine medications (4) Patients for whom Anelem is contraindicated (5) Patients for whom sevoflurane is contraindicated