NIPH Clinical Trials Search

Effect of Simultaneous Injection of Contrast Material and Saline on Image Quality in Contrast-Enhanced CT

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	All conditions requiring body contrast-enhanced CT
Date of first enrollment	17/03/2026
Target sample size	100
Countries of recruitment
Study type	Interventional
Intervention(s)	Written informed consent will be obtained from participants who are considered potentially eligible for this study. Participants will then be randomly assigned to undergo either the conventional contrast injection method (conventional method) or the simultaneous injection of contrast material and saline (simultaneous injection method), which will serve as the control group and the study group, respectively.

Outcome(s)

Primary Outcome	Quantitative evaluation: CT attenuation values, image noise, and signal-to-noise ratio (SNR). Qualitative evaluation: Visual assessment by radiologists, including image quality, lesion and organ conspicuity, and diagnostic performance.
Secondary Outcome	None

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	Not applicable
Gender	Both
Include criteria	1Patients aged 18 years or older at the time of obtaining informed consent (regardless of sex). 2Patients scheduled to undergo contrast-enhanced CT at the time of obtaining informed consent. 3Patients who have provided written informed consent.
Exclude criteria	1Patients weighing over 80 kg at the time of informed consent. 2Patients with a history of allergy-like reactions to contrast media. 3Pregnant patients. 4Patients with eGFR < 30 mL/min/1.73 m2. 5Patients who are deemed unsuitable for participation in this study by the investigator for any other reason.