NIPH Clinical Trials Search

Development of a non-invasive CLDN18.2 methylation biomarker

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	Gastric Cancer
Date of first enrollment	14/07/2025
Target sample size	500
Countries of recruitment
Study type	Observational
Intervention(s)	none

Outcome(s)

Primary Outcome	Correlation between CLDN18.2 expression and CLDN18.2 DNA methylation status in gastric cancer tissues
Secondary Outcome	Correlation with treatment effect

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	Not applicable
Gender	Both
Include criteria	Patients who meet all of the following criteria are eligible: 1. Patients diagnosed with gastric cancer and treated at Yamanashi University Hospital between 2015 and 2027 2. Patients aged 18 years or older
Exclude criteria	Patients who fall into any of the following categories will be excluded from the study: 1. Patients with multiple cancers 2. Patients who are otherwise deemed inappropriate by a physician