NIPH Clinical Trials Search

Evaluation of the impact of temporalis muscle surgical manipulation on oral function in perioperative neurosurgical patients

Basic Information

Recruitment status	Recruiting
Health condition(s) or Problem(s) studied	Patients undergoing neurosurgical surgery
Date of first enrollment	08/05/2026
Target sample size	30
Countries of recruitment
Study type	Observational
Intervention(s)

Outcome(s)

Primary Outcome	Change in occlusal force over time
Secondary Outcome	1. Temporal muscle thickness changes 2. Oral hygiene status 3. Mouth opening 4. Masticatory function 5. FOIS score 6. Blood biochemical parameters 7. Body weight and BMI changes 8. Food intake 9. Clinical outcomes (surgery, complications, hospital stay)

Key inclusion & exclusion criteria

Age minimum	>= 18age old
Age maximum	Not applicable
Gender	Both
Include criteria	1. Adult patients aged 18 years or older. 2. Patients scheduled to undergo neurosurgical surgery at Fukushima Medical University Hospital or Japanese Red Cross Fukushima Hospital after April 2026. 3. Patients able to provide written informed consent before surgery.
Exclude criteria	1. Patients with a history of disease or trauma affecting the oral and maxillofacial region. 2. Patients with dysphagia or swallowing disorders. 3. Patients with cognitive impairment that interferes with study assessments. 4. Patients with diseases causing severe restrictions in nutritional intake (e.g., gastrointestinal obstruction). 5. Patients unable to undergo MRI examination (e.g., pacemaker implantation). 6. Patients considered difficult to follow up (e.g., transfer to another hospital).