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Evaluation of the effects of food intake on oral microbiota.

Basic Information

Recruitment status	Complete: follow-up complete
Health condition(s) or Problem(s) studied	Healthy volunteers
Date of first enrollment	2023/08/27
Target sample size	30
Countries of recruitment	Japan
Study type	Interventional
Intervention(s)	Continuous intake of tablets containing test substance, 3.0 g/day for 4 weeks

Outcome(s)

Primary Outcome	Oral microbiota
Secondary Outcome	Dental caries experience, oral hygiene status (dental plaque, tongue coating), snacking habits

Key inclusion & exclusion criteria

Age minimum	4years-old
Age maximum	5years-old
Gender	Male and Female
Include criteria
Exclude criteria	1)Subjects who consciously use products claiming to be effective, such as test substance. 2)Subjects who regularly use toothpaste claiming that it contains test substance 3)Subjects who have been diagnosed with caries by screening tests 4)Subjects undergoing dental caries treatment 5)Subjects who have declared that they have an allergy to the research food 6)Guardians who are participating in the test of ingesting other foods or medicines, and those who are willing to participate 7)Subjects taking antibiotics or antibacterial agents, or who have taken them within 3 months of the screening test 8)Others who are judged by the investigator to be inappropriate as subjects