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Comparison of efficacy of Teneligliptin and Sitagliptin for glucose fluctuation in Type 2 diabetes

Basic Information

Recruitment status	Complete: follow-up complete
Health condition(s) or Problem(s) studied	Type 2 diabetes
Date of first enrollment	2013/10/01
Target sample size	20
Countries of recruitment	Japan
Study type	Interventional
Intervention(s)	Teneligliptin 20mg/day for 1 week Sitagliptin 50mg/day for 1 week

Outcome(s)

Primary Outcome	Maximum glucose level after supper
Secondary Outcome	AUC over 140 mg/dl after supper 18-24, AUC over 140 mg/dl after supper 20-24, GLP-1 level at 30 minutes after load, IRI level at 2h after load

Key inclusion & exclusion criteria

Age minimum	20years-old
Age maximum	Not applicable
Gender	Male and Female
Include criteria
Exclude criteria	Patients using oral diabetic therapy or insulin therapy, those with mild renal dysfunction (male:s-Cre>1.5, female:s-Cre>1.3), those with severe infectin, those with severe trauma and those with severe liver dysfunction (AST and ALT: 3 times the normal levels) were excluded.